Thursday, August 2, 2012

More men with prostate cancer "team" wait on treatment

Reuters Health - New York | Mon Jul 30, 2012


Men with low-risk forms of prostate cancer are more likely to opt for so-called active surveillance over surgery or radiation when they have a multidisciplinary team of doctors working with them, according to a new study.

Researchers said that may be because teams with urology, imaging and cancer specialists can provide the most balanced view of the risks and benefits of different options.



Read the full Reuters Health report

Monday, July 23, 2012

Mutation Increases Prostate Cancer Risk

Medscape Medical News - July 20, 2012

A new study has confirmed that a genetic mutation significantly increases the risk for prostate cancer, especially early-onset and familial cancers, in white men.

The study was published online July 9 in the Journal of the National Cancer Institute and moves academic research a step closer to a possible commercial test.

The new study comes about 6 months after a groundbreaking article was published on the discovery of the mutation. That article established the G84E mutation as the first major genetic variant associated with inherited prostate cancer.

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Holmium Laser Enucleation Favored for Large Prostate Tumors

Reuters Health:   NEW YORK Jul 05, 2012

In a randomized trial in men with large prostate tumors, Holmium laser enucleation yielded better outcomes than photoselective vaporization.

The study, published online May 16th in The Journal of Urology, involved 80 men with adenomas ranging in size from 62 to 160 mL.

The authors say it's the first randomized head-to-head comparison of Holmium laser enucleation of the prostate (HoLEP) and photoselective vaporization of the prostate (PVP).

Read the full Reuters Health report from Medscape
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Adverse Effects of Prostate Cancer Treatment Persist for Longer Term

In a recent Medscape video article by Dr. Gerald Chodak, a recent study concludes the following:

Compared with men without cancer, men who had been treated with surgery or radiation had significantly worse urinary control, sexual function, and bowel function. Of importance, when patients who had surgery were compared with patients who had radiation, urinary and sexual function were significantly worse in the surgery group, and bowel function was significantly worse in the radiation group.

View the full article here
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Surgery for Prostate Cancer Does Not Save Lives

Reuters Health - NEW YORK | Wed Jul 18, 2012


Prostate cancer surgery didn't appear to save lives compared with observation alone in a new study that tracked men for a decade after their diagnosis.

However, nearly twice as many men who had surgery reported incontinence and impotence after two years, researchers report in the New England Journal of Medicine.

"These are very compelling data," said Dr. Durado Brooks, director of prostate and colorectal cancers at the American Cancer Society, who was not involved in the research.

Both he and study author Dr. Timothy Wilt of the University of Minnesota School of Medicine said the results suggest that many men who have received surgery in the past probably didn't need it.

Read the full Reuters Health report here.

Does Selenium Help to Prevent Prostate Cancer

In today's video, Dr. Gerald Chodak discusses recent studies about the relationship between selenium levels and the risk of developing prostate cancer.


Tuesday, July 17, 2012

Cancer doctors say discuss PSA test with some men

Reuters Health - NEW YORK | Mon Jul 16, 2012


Doctors should discuss prostate cancer screening with men who have at least 10 years left to live, one of the country's largest groups of cancer doctors said Monday.

But men with a poorer outlook should generally avoid screening with the blood test for prostate-specific antigen, or PSA, according to the American Society of Clinical Oncology (ASCO).


"Screening should be discussed with men who have a longer life expectancy, so that men can make an informed decision," said Dr. Ethan Basch, a prostate cancer specialist and co-chair of the ASCO panel.

The new advice, published in the Journal of Clinical Oncology, comes on the heels of a blanket recommendation against prostate cancer screening from the government-backed U.S. Preventive Services Task Force.

When the USPSTF's guidelines were released last May, they triggered an outcry from many cancer specialists and urologists who felt the move could be a death sentence for scores of men across the country.

Dr. Michael LeFevre of the USPSTF stressed the similarities between the two sets of recommendations, but said his organization took a slightly stronger stance against the test.

"We are actually not suggesting that physicians bring up screening with men," he told Reuters Health. If a patient wants the test after getting adequate information about the pros and cons, however, LeFevre said he has no qualms with it.

Read the full Reuters Health report