Tuesday, October 1, 2013

PSA Screening Does More Harm Than Good, Says New Analysis

Medscape Medical News
Roxanne Nelson
Sep 29, 2013

AMSTERDAM — To the ongoing debate over whether routine screening for prostate cancer reduces prostate cancer mortality comes a new analysis that suggests that it does more harm than good.

The total harms that men experience in terms of impotence, incontinence, and other side effects from prostate cancer treatment can severely affect their quality of life, lead author Mathieu Boniol, MD, said here at the European Cancer Conference 2013 (ECCO-ESMO-ESTRO).

Dr. Boniol and colleagues conducted a systematic review of the literature for data on results of prostate-specific antigen (PSA) testing, biopsy rates, and mortality/associated side effects from radical prostatectomy, as well as hospitalization rates associated with biopsy. They also used data from the European Randomized Study of Screening for Prostate Cancer, which is the study showing the most favorable outcomes for PSA screening.


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Testosterone Therapy: Scant Evidence of Benefit in CVD Risk

Medscape Medical News
Steven Fox
Sep 25, 2013

Although there is some evidence that low endogenous testosterone levels may be linked to cardiovascular risk, a review of the last 43 years of literature finds scant definitive evidence that testosterone supplementation affects that risk.

Johannes B. Ruige, MD, PhD, from the Department of Endocrinology, Ghent University Hospital, Belgium, and colleagues. report their findings in an article published online September 24 in the Journal of Clinical Endocrinology & Metabolism.

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